But when the chips are down and you're facing down a rival gang or a 5-star wanted level, which gun can you truly count on? In this guide, we're breaking down the contenders to crown the single best gun in GTA San Andreas.
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The Top Contenders for Best Weapon

The Combat Shotgun (S.P.A.S. 12)
Why it's a contender
Unmatched damage at close range combined with a high rate of fire. It can take down targets with a single, well-aimed blast.
Best for
Clearing buildings, intense close-range shootouts, and stopping charging enemies in their tracks.
How to find it
The Combat Shotgun becomes available at Ammu-Nation after completing the mission "You've Had Your Chips." It also has several spawn locations across the map.
The M4 Assault Rifle
Why it's a contender
It's the jack-of-all-trades. Effective at almost any range, it's the most reliable weapon for any situation you might find yourself in. Hitting the "Hitman" skill level allows you to move and aim with it, making you a walking tank.
Best for
Mid-to-long-range firefights, drive-by shootings (as a passenger), and taking on large groups of enemies.
How to find it
Found at the Los Santos International Airport on the end of a runway, at the K.A.C.C. military fuel depot in Las Venturas, and available for purchase at Ammu-Nation after the mission "Yay Ka-Boom-Boom."
The Desert Eagle
Why it's a contender
The highest damage per shot of any handgun. It's like having a cannon in your pocket.
Best for
When you want to ensure your target goes down and stays down. It's a great backup weapon for precise, powerful shots.
How to find it
You can find one behind a small fence in the Redsands East area of Las Venturas or purchase it at Ammu-Nation after the mission "Black Project."
The Verdict: The Best Gun in GTA San Andreas Is...
While the Combat Shotgun is the undisputed champion of close-range and the Desert Eagle hits like a truck, the M4's sheer versatility makes it the ultimate weapon.
No other gun in the game performs so reliably in so many different scenarios. From picking off distant enemies to surviving an ambush, the M4 is the one gun you can always depend on. Its large ammo capacity and balanced stats mean you're prepared for anything the game throws at you. It is, without a doubt, the true king of the San Andreas arsenal.
Final Thoughts
What do you think is the best gun in GTA San Andreas? The M4 Assault Rifle stands out as the most versatile and reliable weapon in the game, but every player has their own preference based on their playstyle. Want to experiment with different weapons without worrying about ammo? Visit our GTA Cheats page to unlock all weapons instantly and test them out for yourself!

